What Type of Tissue Is the Umbilical Cord Made Of?
Cord Blood Banking
What Is the Umbilical Cord Made Of? The umbilical cord is made up of connective tissue known as Wharton’s Jelly — a gelatinous substance that protects and in
Read Full ArticleIf you or your partner are expecting, chances are that you have at least some knowledge about the placenta and what it does. What may be less clear, though, is whether it's worth considering banking your placental tissue.
The placenta is the temporary organ that acts as a baby's lifeline during pregnancy. It's attached to the wall of the uterus and is connected to the baby via the umbilical cord.
Forming shortly after conception, the placenta provides a fetus with oxygen, nutrients, and growth hormones while removing carbon dioxide and waste. It also passes beneficial antibodies from mother to baby, providing an infant with valuable immunity in the months after birth.
The placenta is delivered shortly after birth. By the time it comes out, it's roughly the size of a small dinner plate and weighs about a pound [*]. The tissue is dark red, bumpy, and rich in blood vessels that resemble the branches of a tree.
In most cases, the placenta is simply discarded after delivery. Placental tissue is a source of stem cells that leads some families to question whether the placental tissue should be collected and banked like cord blood and cord tissue, especially since a few cord blood banks offer the service. But despite what those few banks may say, preserving placental tissue does not offer any known benefits.
Here's what experts have learned about placental stem cells and how they compare to cord tissue stem cells, plus why it isn't worth storing placental tissue for the future.
Stem cells are raw cell material that can grow and change into specialized cells. Placental stem cells are stem cells that have been collected from the tissue of the placenta.
Stem cells can also be derived from sources like cord blood and cord tissue. All of the stem cells derived from the umbilical cord blood and cord tissue are produced during the development of the fetus. However, stem cells taken from placental tissue contain a mix of both fetal and maternal cells and isolating the fetal stem cells from the maternal ones can be very difficult. This may affect the potential usefulness of placenta stem cells.
Only two or three cord blood banks offer the option of banking placental tissue. This uncommon practice involves collecting and storing stem cells from placental tissue. The process happens alongside the collection and storage of cord blood and cord tissue.
After choosing your bank, you'll receive a collection kit that you'll bring along to the hospital when you give birth. After delivering, the placental tissue is collected along with your baby's cord blood and cord tissue, placed in the kit, and transported to the cord blood bank. From there, the cord blood and tissues are tested, processed, and prepared for long-term cryogenic storage.
The few cord blood banks offering placenta tissue banking say that the practice is worthwhile because placenta tissue contains mesenchymal stem cells (MSCs), a type of stem cells not found in cord blood [*]. But placenta tissue stem cells aren't the only source of MSCs. Cord tissue is abundant in MSCs as well, and in fact, the stem cells derived from cord tissue are identical to those taken from placental tissue.
Just as important, the stem cells derived from a baby’s cord tissue are virtually limitless in supply. Cord blood banks have the ability to expand cord tissue cells thousands of times, ensuring that a family won’t run out of cells if they need them. So, there’s no additional benefit to storing placental tissue.
MSCs from cord tissue have also been studied extensively compared to those from placental tissue. While hundreds of clinical trials are studying the use of MSCs from cord tissue, there are no clinical trials looking at the use of MSCs from placental tissue. This means that cord tissue MSCs are much more likely to be used for potential treatment purposes as compared to MSCs from placental tissue. It's also difficult to isolate fetal placental stem cells from their maternal counterparts, which could impact how placental tissue stem cells might be able to be used.
There's also the fact that banking placenta tissue costs families extra money since it’s only sold as an add-on service to cord blood + cord tissue banking. The initial collection, processing, and storage process for placental tissue costs, on average, $800 to $1,300 on top of the costs of storing cord blood + cord tissue [*]. That's a lot to pay for the identical stem cells that can already be obtained from cord tissue, since the cord tissue stem cells can be expanded by thousands of times, providing a virtually unlimited supply of these cells.
In short: Families that opt to bank their baby's cord tissue stem cells are already saving a rich source of MSCs. Banking placental tissue stem cells is simply paying for more of the same. Not only is it an unnecessary and redundant service, it’s also unethical for cord blood banks to offer this “service” since it offers no additional benefits to customers.
If you're already planning on banking your baby's cord blood, it's worth considering banking the cord tissue as well. Here are several reasons why.
Different types of stem cells can be used for different purposes. Cord blood is a rich source of hematopoietic stem cells (HSCs), which are FDA-approved to more than 80 diseases and conditions, including cancers like leukemia and lymphoma, blood disorders like sickle cell disease, and metabolic disorders like Tay-Sachs, to name just a few.
Cord tissue is an abundant source of many different kinds of cells, including mesenchymal stem cells (MSCs), which are different from HSCs found in cord blood. To date, the vast amount of research on the different kinds of cells derived from the cord tissue has been squarely focused on the MSCs or Mesenchymal Stem Cells. MSCs show significant potential in the field of regenerative medicine, and in fact, are currently being studied as a potential treatment in more than 1,600 registered clinical trials [*].
Experts are still learning about the therapeutic effects of MSCs. While research on HSCs has focused primarily on blood and immune system disorders, research on MSCs is geared towards connective tissue disorders and regenerative medicine.
The main benefit of MSCs is thought to come from their potential to exert reparative, anti-inflammatory, and pain-relieving effects on a wide range of injured tissues [*][*]. For instance, research currently looking at MSCs from cord tissue as a regenerative therapy for heart disease has shown that the cells are capable of growing into heart or blood vessel cells, both of which could potentially be used to repair cardiovascular damage caused by a heart attack [*].
Cord blood banks can expand cord tissue cells by thousands of times, ensuring families have as many cord tissue stem cells as they might need. That makes it unnecessary to collect and store additional stem cells from placenta tissue that are identical.
MSCs are currently being studied for their possible use in treating babies as well as siblings or family members in many common diseases that don't yet have a cure. These include: [*]
Cord tissue stem cells offer distinct treatment opportunities compared to stem cells taken from cord blood. Collecting and banking both cord blood and cord tissue means that families have resources to access potential therapies for a wider range of health problems, compared to just banking cord blood stem cells alone.
Cord tissue can be collected, processed, and stored at the same time as cord blood. There's no additional effort needed on the part of families, yet the payback has the potential to be significant.
MiracleCord leads the industry with the most advanced and comprehensive cord blood and cord tissue banking services.
Our highly experienced, state-of-the-art cord blood banking laboratory is FDA-registered and ABAA accredited, and our advanced processing methods have been proven to yield significantly more stem cells compared to other processing methods. Our StemCare thermal cord blood collection kit utilizes a sterile, FDA-approved cord blood collection bag that is safe to use in the sterile field for C-sections.
Just as important, MiracleCord puts families first. We're committed to providing high-quality services at affordable prices and offer a $100,000 quality guarantee ensuring the viability of your baby's cord blood stem cells.
Request a free information kit or enroll today.
MiracleCord doesn’t offer placental tissue banking services for a very good reason: We know this service doesn't offer any additional benefit to our customers.
Some cord blood banks may claim that placenta tissue banking is uniquely valuable, but offering this “service” is unethical as families have access to a virtually unlimited supply of the same stem cells from cord tissue.
In short, saving placental stem cells costs families more money without yielding any additional benefits, so it's best to steer clear.
If you have questions about banking your baby's cord blood or tissue, please feel free to contact us at 888-743-2673 and our cord blood educators will be happy to assist you.
DISCLAIMER: THE INFORMATION ON THIS WEBSITE IS NOT INTENDED TO BE USED AS MEDICAL ADVICE.The materials and information contained on the MiracleCord website is provided for educational and informational purposes only, and is not intended to, and does not constitute, medical or other health advice or diagnosis, and should not be used as such. You should not use this information to diagnose or treat a health problem or disease. If you are seeking personal medical advice, you should consult with a licensed physician. Always consult with a qualified health care provider regarding a medical condition.
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